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[PDF] INHIBITORS OF PROTEIN SYNTHESIS。

Ribosomes are the site of protein synthesis in both prokaryotes and eukaryotes. • These inhibitors work at different stages of translation such as initiation, ...： 。

Inhibitors of protein synthesis identified by a high throughput ...。

We have designed a high throughput screen to identify new inhibitors of eukaryotic protein synthesis. We used a bicistronic mRNA reporter to multiplex our ...。

Cordycepin Inhibits Protein Synthesis and Cell Adhesion through ...。

Furthermore, we observed a strong inhibition of total protein synthesis that ... In 4EBP knock-out cells, the effect of cordycepin on translation is ...。

Ribosomes and Protein Synthesis - Rockefeller University Press。

that the proteins of the ribosomes are involved in the many individual steps of protein synthesis; however, the function of ribosomal RNA is still elusive.。

Mechanism and Regulation of Protein Synthesis in Saccharomyces ...。

2016年5月3日 · The mechanism of protein synthesis is well conserved between yeast and other ... While mutational inactivation of Ded1 inhibits translation ...。

Discovery and Analysis of Natural-Product Compounds Inhibiting ...。

We have developed a poly(U) mRNA-directed aminoacylation/translation (A/T) protein synthesis system composed of phenylalanyl-tRNA synthetases (PheRS), ribosomes ...： tw | tw。

Cell-type-specific drug-inducible protein synthesis inhibition ... - Nature。

2020年1月20日 · New protein synthesis is known to be required for the consolidation of memories, yet existing methods of blocking translation lack ...。

Translation initiation factor modifications and the regulation ... - Nature。

The rate of protein synthesis is rapidly down-regulated in mammalian cells following the induction of apoptosis. Inhibition occurs at the level of polypeptide ...。

mRNA-to-protein translation in hypoxia | Molecular Cancer | Full Text。

2019年3月30日 · Additionally, HIFα transcriptional activity is inhibited in normoxia by an asparagine hydroxylase, factor-inhibiting hypoxia-inducible factor ( ...： tw | tw。

Full article: Tuning protein synthesis for cancer therapy - Taylor ...。

2021年2月22日 · Furthermore, Kras mutation completely removed the efficacy of rapamycin as an inhibitor of proliferation in Apc-deficient cells, both in ...